European ADHD Guideline Group (EAGG)
The European ADHD Guidelines Group is a part of EUNETHYDIS set up to serve “the provision of evidence based clinical recommendations”. It therefore seeks to apply reliable scientific knowledge to help decision-makers, service users and practitioners in making well-informed judgements about how to improve the management of people affected by ADHD.
This over-riding goal involves making reviews, recommendations and guidelines, and identifying gaps in the science base. It does so, in the general spirit of EUNETHYDIS, by acting as a co-operative group of scientific and clinical disciplines, where knowledge is disseminated in an atmosphere of trust, loyalty, and mutual respect. It will maintain high ethical standards in its activities.
EAGG Members
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Associate Prof. Baeyens, Dieter (Belgium)
Research Unit Parenting and Special Education,
Faculty of Psychology and Educational Sciences,
KU Leuven, Belgium
https://ppw.kuleuven.be/pserg/psergstaff/00062782
Work and interestsDieter Baeyens is associate professor at the research unit Parenting and Special Education of KU Leuven. He is a registered clinical psychologist and behavior therapist. His research consists of two research lines aiming to develop and test interventions in health care and educational settings. His first research line focuses on the role of contextual factors (e.g. parenting, teacher-student interactions) in the development of executive functions in children and adolescents with and without ADHD, across different cultures. A second research line focuses on transitional care and intervention studies for individuals with ADHD and autism spectrum disorder in young adulthood (e.g., effect of reasonable accommodations, guidelines for transitional care). In his research, Baeyens combines a wide range of methods and designs: meta-analysis and –regression, experiments, intervention research (microtrials, RCT), psychometric studies for questionnaire development, and mixed-methods approaches. The valorization of his work includes development of ADHD questionnaires, intervention manuals (e.g., CBT for adults with ADHD) and books for professionals. Baeyens is chair of the Social and Societal Ethics Committee of KU Leuven. He is also the former coordinator of the section Special Educational Needs of the European Association for Research on Learning and Instruction (EARLI) (2015-2019). He is current member of the advisory board of ZitStil, the Flemish expertise center on ADHD, and of ICF Belgium. As an active member of the European Adult ADHD Network, he co-authored the European consensus statement on adult ADHD (2019). He co-heads with Saskia van der Oord the ADHD team of PraxisP, the intervention center of the Faculty of Psychology and Educational Sciences of KU Leuven.
Declaration of potential conflict of interestsN/A
Contact info -
Prof. Banaschewski, Tobias (Germany)
Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim
https://www.zi-mannheim.de/en/research/departments-research-groups-institutes/child-adolescent-psychiatry-psychotherapy-e.html
https://www.zi-mannheim.de/en/patient-care/department-child-adolescent-psychiatry-psychotherapy.html
Work and interestsPsychopathology, neuropsychology, neurophysiology, and psychopharmacology of ADHD and comorbid disorders.
Declaration of potential conflict of interests12.08.2021
During the last three years TB served in an advisory or consultancy role for ADHS digital, Infectopharm, Lundbeck, Medice, Neurim Pharmaceuticals, Oberberg GmbH, Roche, and Takeda.
He received conference support or speaker’s fee by Medice and Takeda.
He received royalities from Hogrefe, Kohlhammer, CIP Medien, Oxford University Press.Contact info -
Prof. PhD. Bölte, Sven (Sweden)
Center of Neurodevelopmental Disorders (KIND), Centre for Psychiatry Research;
Department of Women’s and Children’s Health, Karolinska Institutet &
Child and Adolescent Psychiatry, Stockholm Health Care Services, Stockholm County Council
Work and interestsSven Bölte, Ph.D., is professor of child and adolescent psychiatric science at the Department of Women’s and Children’s Health, Karolinska Institutet (KI), and senior clinical psychologist at the Division of Child and Adolescent Psychiatry, Center for Psychiatry Research, Stockholm County Council, Sweden. He is director of the KI Center of Neurodevelopmental Disorders (“KIND”), editor of AUTISM, The Scandinavian Journal of Child and Adolescent Psychology and Psychiatry, and associate editor of the Journal of Autism and Developmental Disorders, and Child and Adolescent Psychiatry and Mental Health.
He is among other things founder of the Scientific Society Autism Spectrum (www.wgas.org) and international ADOS and ADI-R trainer. For his work, he has received several recognitions, such as the ”Life Watch Nordiska Priset”, ”Årets Ljus” (Society Attention), Psynk award GNET” (Sweden’s Municipalities & Regions), Autism CRC (Australia) Achievement in Autism Research and ”Fellow of the International Society for Autism Research” (INSAR). Professor Bölte has published more than 400 original articles, reviews, book chapters, assessment and intervention tools in the field of autism spectrum, ADHD, and other neurodevelopmental conditions, and has been cited more than 21,000 times (H-index 70).Declaration of potential conflict of interestsBölte discloses that he has in the last 3 years acted as an author, consultant or lecturer for Medice and Roche.
He receives royalties for textbooks and diagnostic tools from Hogrefe, Kohlhammer and UTB. Bölte is shareholder in SB Education/Psychological Consulting AB and NeuroSupportSolutions International AB.Contact info -
Prof. Brandeis, Daniel (Germany)
Departments of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health Mannheim, and University of Zurich
Work and interestsNeurophysiology, multimodal brain mapping and imaging of developmental trajectories and plasticity in child and adolescent psychiatry, longitudinal and multicenter studies, disorder-specific and transdiagnostic pathophysiological brain mechanisms, state regulation, attention, inhibition, sleep and ADHD, reading acquisition and dyslexia, aggression, neuroscience based biomarkers for stratification and prediction, clinical translation into prevention and innovative personalized treatments, neurofeedback and biofeedback RCTs, metaanalyses, ecological assessment and treatment, imaging genetics, gene x environment interactions.
Declaration of potential conflict of interestsServed as an unpaid scientific committee member in a EU-funded neurofeedback trial.
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Prof. Buitelaar, Jan K. (Netherlands)
Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behaviour, Radboudumc;
Karakter Child and Adolescent Psychiatry
http://orcid.org/0000-0001-8288-7757
Work and interestsJan Buitelaar is an emeritus professor of psychiatry and child and adolescent psychiatry at the Radboud University Medical Centre, and at the Donders Institute for Brain, Cognition and Behaviour in Nijmegen, The Netherlands. He has a strong clinical and research interest in neuropsychiatric disorders as ADHD, autism and impulsivity and aggression related disorders, and is involved in pharmacological, cognitive, clinical, genetic, and neuroimaging studies in these disorders. His current active research is focused on translational studies aiming to identify new molecular targets for ADHD and autism through matching preclinical models to human imaging genetics studies. His research is supported by numerous grants from the European Union, NIH, and from the Dutch Medical Research Council.
Declaration of potential conflict of interestsJan Buitelaar has been in the past 3 years a consultant to / member of advisory board of / and/or speaker for Takeda/Shire, Roche, Medice, Novartis, Angelini, Janssen, and Servier. He is not an employee of any of these companies, and not a stock shareholder of any of these companies. He has no other financial or material support, including expert testimony, patents, royalties.
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MD. PhD. Carucci, Sara (Italy)
1. Dept. Biomedical Sciences, Sect. Neuroscience & Clinical Pharmacology, University of Cagliari, Cagliari, Italy;
2. Child & Adolescent Neuropsychiatry Unit, “A.Cao” Paediatric Hospital, “G.Brotzu”, Hospital Trust, Cagliari Italy.
Work and interestsI am a Senior Consultant Child and Adolescent Neuropsychiatrist in the Child & Adolescent Neuropsychiatry Unit at the "A.Cao" Paediatric Hospital, "G.Brotzu", Hospital Trust, in Cagliari, Italy, with clinical experience in neuropsychiatric disorders with particular attention to neurodevelopmental conditions such as ADHD, Mood Disorders and Disruptive, Impulse-Control and Conduct Disorders.
My main research activities are focused on the efficacy and safety of medications for children and adolescents in psychiatric disorders including ADHD and Conduct Disorder. In 2016 I completed my PhD program in Neuroscience on the long-term effects of Methylphenidate in ADHD children and adolescents at the University of Cagliari. I collaborated on several FP-7 projects on child and adolescent Mental Health, and I am currently involved in many no profit independent studies on ADHD and other neurodevelopmental disorder as well as in Industry-supported European registrative trials for innovative medications in paediatric psychopharmacology. I also have a special interest in implementing research knowledge into routine clinical practice with the aim to meet the needs of the young patients in the clinical real world.Declaration of potential conflict of interestsCollaborations within projects from the European Union (7th Framework Program) and in sponsored clinical trials by Shire Pharmaceutical Company, Lundbeck, Otsuka, Janssen Cilag and Angelini.
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Prof. Coghill, David (Australia)
Professor of Child and Adolescent Psychiatry, Royal Children’s Hospital Melbourne, Financial Markets Foundation, Chair of Developmental Mental Health, Departments of Paediatrics and Psychiatry
https://findanexpert.unimelb.edu.au/profile/773808-dave-coghill
Work and interestsDave Coghill is a child and adolescent psychiatrist by training. His research focuses on developing a better understanding of the pathophysiology of ADHD, conduct disorder and depression using a range of approaches including neuropsychopharmacology, neuroimaging and genetics and developing and personalising approaches to the treatment of child and adolescent mental health problems through the development of biomarkers, neurocognitive phenotypes, clinical trials, pharmacoepidemiology and patient reported outcomes. He has maintained a strong clinical presence and has worked hard to develop clinical pathways that facilitate the rapid transfer of research evidence into routine clinical practice. In addition to his academic role at the University of Melbourne where he is Deputy Head of the Department of Paediatrics, he is part of the neurodevelopmental disorders team at The Royal Children’s Hospital, Melbourne.
Declaration of potential conflict of interestsDavid Coghill has received research support and/or honoraria from Shire/Takeda, Medice, Novartis and Servier and royalties from Oxford University Press and Cambridge University Press.
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Prof. Cortese, Samuele (United Kingdom)
University of Southampton;
The EAGG chair
https://www.southampton.ac.uk/psychology/about/staff/sc6r14.page
Work and interestsMy research aims to inform clinical decision making in child and adolescent psychiatry, with a specific focus on ADHD (and its related neurodevelopmental conditions), and sleep disorders. My studies are mainly based on advanced meta-analytic approaches, as well as large epidemiological datasets.
Declaration of potential conflict of interestsPast 5 years: Samuele Cortese declares honoraria and reimbursement for travel and accommodation expenses for lectures from the following non-profit associations: Association for Child and Adolescent Central Health (ACAMH), Canadian ADHD Alliance Resource (CADDRA), British Association of Pharmacology (BAP), and from Healthcare Convention for educational activity on ADHD.
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Prof. Daley, David (United Kingdom)
Academic Unit of Mental Health & Clinical Neurosciences, School of Medicine, University of Nottingham;
MindTech NIHR MedTech Mental Health Cooperative and Centre for ADHD and Neurodevelopmental disorders;
Across the Lifespan CANDAL, Institute of Mental Health, University of Nottingham.
https://www.nottingham.ac.uk/medicine/people/david.daley
Work and interestsDavid Daley is Professor of Psychological Intervention and Behaviour Change within the Academic Unit of Mental Health and Clinical Neurosciences, school of Medicine at the University of Nottingham, Uk.
He received his B.A. in Applied Psychology from the National University of Ireland University College Cork and his Ph.D. in Developmental Psychopathology from the University of Southampton, UK.
His research interests are focused on non-shared environmental influences on ADHD; in particular he has devoted much of his career to the study of factors that enhance and interfere with the effective and enjoyable parenting of children with ADHD. He is internationally recognized as an expert in the development and evaluation of psychological interventions for families of children with ADHD.Declaration of potential conflict of interestsProfessor Daley reports grants, personal fees, non-financial support and other from Shire/Takeda, and non-financial support from Medice, non-financial support from Qb Tech, other from Hachette in the form of royalities from the self help version of the New Forest Parent Training Programme and other from New Forest Parent Training Programme in form of fees for the provision of training and supervision in the New Forest Parent Training Programme.
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Prof. Dr. Döpfner, Manfred (Germany)
Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy; Faculty of Medicine and University Hospital Cologne, University of Cologne, Germany;
School of Child and Adolescent Cognitive Behavior Therapy (AKiP), Faculty of Medicine and University Hospital Cologne, University of Cologne, Germany;
Department of Psychology, Faculty of Human Sciences, University of Cologne, Germany
https://akip.uk-koeln.de/
Work and interestsManfred Döpfner is director of the School for Child and Adolescent Cognitive Behavior Therapy at the University of Cologne. He is supervisor in cognitive behaviour therapy. He received the German Psychology Prize for his scientific work in 2005.
His main research interests are assessment, prevention, and treatment of ADHD, Conduct Disorders, Anxiety Disorders, Obsessive Compulsive Disorders and Tic Disorders. He is principal investigator of several multicenter trials on the effects of prevention, cognitive behavior therapy (including self-help interventions and digital interventions), and pharmacotherapy for children with ADHD and other externalizing disorders.Declaration of potential conflict of interestsManfred Döpfner received consulting income and research support from Lilly, Medice, Takeda, and eyelevel GmbH and research support from the German Research Foundation, German Ministry of Education and Research, German Ministry of Health, and Innovation Fund. He received income as head, supervisor, and lecturer of the School of Child and Adolescent Cognitive Behaviour Therapy at the University Hospital Cologne and as consultant for Child Behaviour Therapy at the National Association of Statutory Health Insurance Physicians (Kassenärztliche Bundesvereinigung). He also received royalties from treatment manuals, books and psychological tests published by Beltz, Elsevier, Enke, Guilford, Hogrefe, Huber, Kohlhammer, Schattauer, Springer, Wiley.
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Dr. Ferrin, Maite (United Kingdom)
Barnet Enfield and Haringey NHS Trust and Recognition Health London, UK
Work and interestsConsultant Child and Adolescent Psychiatrist with special interest in psychoeducation of families of young people with ADHD.
Declaration of potential conflict of interestsPayment By Medice for presenting in conferences in 2019, 2021 and 2022 and by Rovi for conferences in 2020,2021 and 2022. Advisory board for Novartis in 2020. PI for Servier for Phase 3 study on Bumetanide for severe ASD.
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Prof. MD. PhD. Galera, Cedric (France)
Université de Bordeaux, Bordeaux Population Health Center INSERM, Centre Hospitalier Perrens, Bordeaux, France
Work and interestsCédric Galera is professor of Child and adolescent Psychiatry at the Bordeaux University Hospital. Doctor in epidemiology, he leads a research team dedicated to youth mental health at the Bordeaux Population Health Center (INSERM 1219).
His work aims at (1) Understanding the risk and protective factors of Mental, Neurological and Substance use problems in young people using a lifespan perspective and (2) Test the efficacy of strategies to prevent Mental, Neurological and Substance use problems and build resilience to stressors in youths / parents.Declaration of potential conflict of interestsN/A
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Prof. Hollis, Chris (United Kingdom)
Mental Health & Clinical Neuroscience, University of Nottingham & NIHR MindTech MedTech Co-Operative
https://www.nottingham.ac.uk/medicine/people/chris.hollis
Work and interestsChris Hollis is Professor of Child & Adolescent Psychiatry at the University of Nottingham, Director of the NIHR MindTech MedTech Co-operative and leads the NIHR Nottingham BRC Mental Health and Technology Theme. He is Principal Investigator on the HTA ORBIT (Online Remote Behavioural Intervention for Tics) trial (Hollis et al. Lancet Psychiatry. 2021 Oct; 8(10):871-882) and co-leads the £4M MRC programme award ‘Adolescent Mental Health in the Digital World’. He led the AQUA trial of QbTest for ADHD (Hollis et al. Journal of Child Psychology and Psychiatry. 2018 Dec;59(12):1298-1308) which is now supported by the National AHSN ADHD Focus Programme for widespread NHS adoption.
Chris trained in psychiatry at the Maudsley Hospital and Institute of Psychiatry, where he was awarded an MRC Training Fellowship and completed his PhD on the long-term adult outcome adolescent-onset psychosis. He works as a Consultant in Developmental Neuropsychiatry with Nottinghamshire Healthcare NHS Foundation Trust and leads a regional lifespan neurodevelopmental service at Queen’s Medical Centre, Nottingham. His clinical and research interests include ADHD, Tourette syndrome, early onset schizophrenia and the development, evaluation and implementation of digital technologies to support better mental health.
As Director of MindTech, Chris is passionate about harnessing digital technology and building its evidence-base in mental healthcare by bringing together patients, clinicians, academics and technology developers. In 2020, Chris was a contributor to the 2020 World Innovation Summit for Health (WISH) report: The digital mental health revolution: Transforming care through innovation and scale-up. He was the recipient of the Association of Child of Child & Adolescent Mental Health (ACAMH) Digital Innovation Award 2020. He recently led the James Lind Alliance priority Setting Partnership’s Top 10 research priorities for digital technology in mental healthcare (Hollis et al. Lancet Psychiatry. 2018 Oct;5(10):845-854). Chris chaired the NICE Guideline for schizophrenia and psychosis in children and young people (2011-13) and was a member of the 2018 NICE ADHD (Update) Guideline Committee. In 2015, Chris received a prestigious NIHR Senior Investigator Award. This distinguished accolade was awarded for a further 4 years in April 2019.Declaration of potential conflict of interestsMember of the 2018 NICE ADHD (Update) Guideline Committee
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Prof. Holtmann, Martin (Germany)
LWL-University Hospital for Child and Adolescent Psychiatry, Ruhr-University Bochum
Work and interests- ADHD: comorbidity with affective disorders and SUD;
- non-pharmacological treatments for ADHD, affective disorders, and SUD;
- clinical picture, course and treatment of bipolar disorder and severe mood dysregulation/DMDDDeclaration of potential conflict of interestsMartin Holtmann served in an advisory role for Shire, Takeda and Medice and received conference attendance support or was paid for public speaking by Medice, Shire and Neuroconn.
He received research support from the German Research Foundation and the German Ministry of Education and Research.
He received royalties as Editor-in-Chief of the German Journal for Child and Adolescent Psychiatry and for textbooks from Hogrefe.Contact info -
Dr. Nagy, Peter (Hungary)
Division of Neurodevelopmental Disorders, Bethesda Children's Hospital, Budapest, Hungary
Work and interestsI have been fascinated with child psychiatry ever since I first heard about it. My first job after completing medical school was at Hungary’s only dedicated child psychiatric clinic, which was the first place in the country to begin offering comprehensive services to children with Tourette’s syndrome. Tourette’s was the first neurodevelopmental disorder I encountered as a young doctor, and I was amazed by the interplay of the infinitely complex central nervous system and the environment. Later, my work and therefore my experience expanded to other neurodevelopmental disorders, most notably, ADHD. When several years later, I became the director of this clinic, I made it a top priority to add quality research to patient care, and we participated in many national and international studies on ADHD, Tourette’s, OCD, and ASD. After 8 years in management, I decided to focus all my time on clinical work and research, so I switched jobs and now I am chief of the neurodevelopmental unit at Bethesda Children’s Hospital, Budapest, Hungary.
Declaration of potential conflict of interestsI have received occasional remuneration to serve on the advisory board for Eli Lilly and Co. and MEDICE Arzneimittel Pütter GmbH & Co. I have participated in clinical studies focusing on various neurodevelopmental disorders funded by pharmaceutical companies (Shire, Otsuka, Servier).
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Prof. Purper-Ouakil , Diane (France)
University Hospital of Montpellier, Department of Child and Adolescent Psychiatry, University of Montpellier;
CEAND, INSERM U 1018 UVSQ, Psychiatry, Development and Trajectories
Work and interestsClinical and teaching activities:
Professor of child and adolescent psychiatry at the university hospital of Montpellier, France since 2011 and head of the child and adolescent unit of the Saint Eloi Hospital. This unit has facilities for both inpatient and outpatient care for young patients and has specialized services for children and adolescents with ADHD and eating disorders.
Medical director of a trust of CAMHS and AMHS services within the CHU of Montpellier beween 2016 and 2019.
Current vice-president of the national faculty college of psychiatry involved in the ongoing reform of the training curriculum of medical studies and member of the professional college of psychiatrists.
Research topics:
• development of the evidence-base of psychological, neurophysiological and pharmacological treatments, especially in ADHD and emotional disorders.
• involvement in collaborative treatment studies, some assessing parent programs, an important feature of comprehensive treatment plans for young people with complex needs.
Network activities:
• vice-chair of the ECNP child and adolescent network; c4c member, member of the network “Institut de Psychiatrie”; member of the French professional college of psychiatrists, member of the National Health Conference, expert for the National Health Authority (HAS)
Main collaborative projects:
• FP7, H2020 SME, F-CRIN, national PHRCDeclaration of potential conflict of interests01/2019 speaker fee from Shire, unpaid scientific collaboration with Mensia (scientific coordination of the Newrofeed study)
02/2019-02/2022 non-financial support from HAC Pharma, Medice, Lundbeck SASContact info -
Prof. Ramos-Quiroga, J. Antoni (Spain)
Department of Psychiatry at Hospital Universitari Vall d’Hebron (HUVH), Barcelona, Spain.
Department of Psychiatry and Legal Medicine, Barcelona Autonomous University, Barcelona, Spain.
Vall d’Hebron Research Institute (VHIR) , Barcelona, Spain.
https://www.doctorramosquiroga.com/
https://hospital.vallhebron.com/es/profesionales/josep-antoni-ramos-quiroga
Work and interestsProfessor Ramos-Quiroga (orcid: 0000-0003-1622-0350), has published more than 270 articles in the field of genetics, psychopharmacology, neurodevelopmental disorders and depression (h-index: 57 and more than 16,500 citations). He is also VHIR’s Principal Investigator in seven European grants (Horizon 2020) focused on treatment-resistant depression, ADHD and autism. Dr. Ramos-Quiroga was one of the founders of International Collaboration on ADHD and Substance Abuse (ICASA) and he is member of the board of ICASA Foundation. Also, he is member of several international consortiums focused on mood disorders and neurodevelopmental disorders (IMpACT, PGC, ENIGMA, ADHD-ECNP Network).
Declaration of potential conflict of interestsJ.A.R.Q was on the speakers’ bureau and/or acted as consultant for Janssen-Cilag, Novartis, Shire, Takeda, Bial, Shionogi, Sincrolab, Novartis, BMS, Medice, Rubió, Uriach, Technofarma and Raffo in the last 3 years. He also received travel awards (air tickets + hotel) for taking part in psychiatric meetings from Janssen-Cilag, Rubió, Shire, Takeda, Shionogi, Bial and Medice. The Department of Psychiatry chaired by him received unrestricted educational and research support from the following companies in the last 3 years: Janssen- Cilag, Shire, Oryzon, Roche, Psious, and Rubió.
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Prof. Romanos, Marcel (Germany)
University Hospital Würzburg, Center of Mental Health, Dep. of Child and Adolescent Psychiatry, Psychosomatics Psychotherapy, Würzburg, Germany
https://www.ukw.de/child-and-adolescent-psychiatry-psychotherapy-and-psychosomatics/research/
Work and interestsMy initial interest in ADHD research was on genetics and neurobiology by investigateing large pedigrees with high density of ADHD. Aiming to translate neurobiological findings to clinical service I evaluated putative biomarkers of ADHD and participated in large multicenter therapy studies. Recently my focus broadened with respect to assessing the quality and availability of clinical services. I have established a longstanding relationship with the German ADHD self-help organization. Apart fron ADHD my research interests pertain to anxiety disorders and evidence-based prevention mental disorders in childhood and adolescence.
Declaration of potential conflict of interestsWithin the last 10 years I have not had any direct or indirect financial relation with the pharma-industry. I have contributed as writer and editor to ADHD psychotherapy manuals and psychopharmacology books. My research is funded by official agencies such as the DFG, BMBF, Innvationsfonds, Ministries etc. I am member of several organizations and associations, e.g. president-elect of the German Association of Child and Adolescent Psychiatry.
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Prof. Santosh, Paramala J. (United Kingdom)
Department of Child & Adolescent Psychiatry, Institute of Psychiatry, Psychology & Neuroscience, King’s College London;
South London & Maudsley NHS Foundation Trust
https://kclpure.kcl.ac.uk/portal/en/persons/paramala-santosh(e07bc161-4618-4664-9fb5-afe6c1194a97).html
Work and interestsProfessor Paramala Santosh is a Consultant Child & Adolescent Psychiatrist at the Maudsley Hospital, and a Professor in Developmental Neuropsychiatry and Psychopharmacology at the Institute of Psychiatry, Psychology & Neurosciences (IoPPN), King's College London. He developed and heads the national and specialist Centre for Interventional Paediatric Psychopharmacology and Rare Diseases (CIPPRD), and the CIPP Rett Centre. The CIPP Rett Centre is the world's first centre for personalised medicine in Rett Syndrome that focuses on developing digital health strategies to monitor and manage patients whilst conducting translational research using the HealthTrackerTM platform, providing holistic specialist care, and conducting clinical trials. Professor Santosh also co-developed the GDPR compliant HealthTrackerTM platform for remote screening, patient reported outcome monitoring, and structured medication review and is the CEO of the SME HealthTracker Ltd. Professor Santosh is an internationally recognised expert in ADHD, ASD, paediatric psychopharmacology, treatment-resistant developmental multimorbidity, and neuropsychiatric problems in acquired brain injury, childhood dementias, and rare diseases such as Rett syndrome, Septo-Optic Dysplasia, Mucopolysaccharidoses, and paediatric neurodegeneration. His research focusses on translational personalised medicine approaches using remote digital health monitoring, structured pharmacological approaches, sensor-based psychophysiological monitoring, and machine learning.
Declaration of potential conflict of interestsProfessor Santosh is the co-inventor of the HealthTrackerTM and is the Chief Executive Officer and shareholder in HealthTracker Ltd.
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Prof. Simonoff, Emily (United Kingdom)
Department of Child & Adolescent Psychiatry, Institute of Psychiatry, Psychology & Neuroscience, King’s College London
https://kclpure.kcl.ac.uk/portal/emily.simonoff.html
Work and interestsEmily Simonoff is Professor of Child and Adolescent Psychiatry at the Institute of Psychiatry, Psychology and Neuroscience, King's College London, where she is also head of the Department. She is also academic lead for the Child and Adolescent Mental Health Services Clinical Academic Group at the South London and Maudsley Foundation Trust. She in a UK National Institute of Health Research Senior Investigator. She was the Senior Clinical Advisor to the National Institute of Health and Clinical Excellence (NICE) on the 2018 ADHD guidelines and is currently a member of the ICHOM Standard Set for Neurodevelopmental Disorders Advisory Group. She chairs the EAGG since 2015. Emily's interests span a range of neurodevelopmental disorders. She has also been a member of the two NICE Guidelines groups for autism and a member of the Strategy Board for the UK National Autism Project. She has been a member of the Westminster Commission for Autism and has given evidence to the All-Party Parliamentary Group on Autism. Emily receives research funding related to autism from the Medical Research Council, Economic and Social Research Council, National Institute of Health and Research EU Innovative Medicines Initiative, amongst other organization. She is a consultant child and adolescent psychiatrist in the Maudsley-based Service for Complex Autism and Associated Neurodevelopmental Disorders, funded by NHS England to see children and young people across the southern region with complex presentations.
Declaration of potential conflict of interestsGrant funding over the last 5 years from the K National Institute for Health Research, Medical Research Council, Economic and Social Research Council, Charity, Mudsley Charity and the European Union Innovative Medicines Initiative.
Simonoff has developed the app Molehill Mountain for the management of anxiety in autistic people.Contact info -
Prof. Sonuga-Barke, Edmund (United Kingdom)
Department of Child & Adolescent Psychiatry, Institute of Psychiatry, Psychology & Neuroscience, King’s College London
https://www.kcl.ac.uk/people/edmund-sonuga-barke
Work and interestsSonuga-Barke is an academic developmental psychologist (non-clinician) and currently Professor of Developmental Psychology, Psychiatry and Neuroscience at the Institute of Psychology, Psychiatry and Neuroscience, Kings College London. He is Honorary Skou Professor at Aarhus University School of Medicine, Denmark. He is Editor-in-Chief of the Journal of Child Psychology and Psychiatry.
Motivated by his own experience as a child growing up with learning difficulties his research focuses on improving the lives of children and adolescents with neuro-developmental disorders - especially ADHD. To this end, his work aims to develop new therapeutic approaches by employing basic developmental science approaches to study the pathogenesis of such conditions, their underlying genetic and environmental risk and resilience sources and their mediating brain mechanisms and developmental and mental health outcomes.
He has led the series of EAGG meta-analyses of non-pharmacological approaches to ADHD treatments.
Sonuga-Barke is a Fellow of the Academy of Medical Sciences (2016) and The British Academy (2018).Declaration of potential conflict of interestsIn the last three years he has given paid talks for Medice and Shire(Takida). He has been a consultant for Neurotech Solutions International. He currently holds grant funding from QBTech. He receives an annual honorarium from the JCPP.
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Prof. MD. PhD. Soutullo, Cesar (United States)
Director, ADHD Outpatient Program. Louis A. Faillace MD Department of Psychiatry & Behavioral Sciences. McGovern
Medical School, The University of Texas Health Science Center at Houston, Texas, USA
https://www.ncbi.nlm.nih.gov/pubmed/?term=Soutullo+C
https://scholar.google.com/citations?hl=es&user=No-3YcMAAAAJ
Work and interestsChild & Adolescent Psychopharmacology and Phenomenology of ADHD an Mood disorders.
Early detection and treatment optimization, adherence and maintenance of full response in children and adolescents with ADHD.
Mentoring & teaching students, residents, fellows, nurses, social worker, etc in an interdisciplinary team.Declaration of potential conflict of interests2018-2021:
Research funds for his department (non-personal):
• Texas Child Mental Health Care Consortium (Youth Depression & Suicide Network) SB11
• Lundbeck
Consultant / Advisory Board:
• Editorial Médica Panamericana - Spain
• NeuroTech Solutions Ltd - Israel
• Limbix Health - USA
• Shire / Takeda - Europe & Spain
Speaker's Bureau / CME talks (not about a product):
• Bial - Portugal
• Medice - Germany
• Rubio – Spain
• Shire/ Takeda - Europe & Spain
Royalties:
• Editorial Médica Panamericana - SpainContact info -
Prof. Steinhausen, Hans-Christoph (Switzerland)
Department of Child and Adolescent Psychiatry, Psychiatric University Hospital Zurich, Switzerland
https://www.kjpd.uzh.ch/de/aboutus/Geschichte/Ehemalige-%C3%84rztliche-Direktoren.html
Work and interestsDevelopmental psychopathology and epidemiology, neuropsychiatry and genetics, clinical psychopharmacology, evaluation research.
Declaration of potential conflict of interestsIn the last 36 months, H.-C. Steinhausen has worked as a speaker for Medice and has received book royalties from Cambridge University Press, Elsevier, Hogrefe, Huber, Klett, and Kohlhammer publishers.
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Prof. Stringaris, Argyris (United Kingdom)
Department of Epidemiology and Applied Clinical Research, Division of Psychiatry, University College London, London, UK;
Section of Clinical and Computational Psychiatry (Comp), Emotion and Development Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA
Work and interestsI am the Professor of Child and Adolescent Psychiatry at UCL and head the Mood in Neurodevelopment (MIND) Unit at UCL. As a Clinician Scientist, I study mood and the mechanisms that lead to depression, particularly in adolescents. I am learning from my patients, my colleagues, but also from disciplines outside my own, such as philosophy, history, computer science and neurology. My clinical interest is in depression and severe irritability (emotion dysregulation).
I was until recently Senior Investigator and Chief of the Section of Clinical and Computational Psychiatry at NIMH/NIH in the USA and before that a Senior Lecturer and a Wellcome Trust Fellow at the Institute of Psychiatry Psychology and Neuroscience, King's College London. I trained in Child and Adolescent Psychiatry at the Maudsley Hospital. I am the President of the International Society for Research in Child and Adolescent Psychiatry.
Recent insights from our laboratory include:
• How the timing of events influences the way we feel
• The Phenomenon of Passage of Time Dysphoria and how it affects psychological tasks.
• The limited ability of MRI to predict suicidality in young people.
• Use of magnetoencephalography to describe reward and mood dynamics in the brain.
• How to treat severe irritability in youth.
I am also very excited about our current and upcoming work on:
• How power relationships shape emotional responses.
• Statistical approaches to capturing adolescents’ preferences for treatment.Declaration of potential conflict of interestsProfessor Stringaris' research influenced the DSM-5 decisions on dimensions of ODD and the recognition of irritability as a source of impairment in children and adolescents. He has developed the Affective Reactivity Index a measure of irritability with colleagues from KCL and NIH. He was also co-developer of the Coronavirus Impact Survey (CRISIS), a measure of the effects of the covid pandemic on mental and physical health.
He is an Editor for European Child and Adolescent Psychiatry, a former Associate Editor of Journal of Child Psychology and Psychiatry, President of the International Society for Child and Adolescent Psychopathology. One of his most recent projects involved the co-development with Dr Hanna Keren of a mood-machine interface device to modulate mood states.Contact info -
Prof. Thapar, Anita (United Kingdom)
Department of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University
https://www.cardiff.ac.uk/people/view/126769-thapar-anita
Work and interestsI conduct epidemiological, genetic and clincal research on ADHD and additional neurodevelopmental disorders (e.g. autism spectrum disorder) as well as depression from 0 to 25 years.
Declaration of potential conflict of interestsN/A
Contact info -
Prof. Dr. van den Hoofdakker, Barbara J. (The Netherlands)
1. University of Groningen, University Medical Center Groningen, Department of Child and Adolescent Psychiatry, Groningen, The Netherlands;
Accare Child Study Center, Groningen, The Netherlands;
University of Groningen, Department of Clinical Psychology and Experimental Psychopathology, Groningen, The Netherlands
2. Accare Child Study Center, Groningen, The Netherlands
3. University of Groningen, Department of Clinical Psychology and Experimental Psychopathology, Groningen, The Netherlands
Work and interestsI work as a special professor and clinical psychologist at Accare, a large Dutch child and adolescent mental health and research organization, and at the University of Groningen (Departments of Child and Adolescent Psychiatry and of Clinical Psychology and Experimental Psychopathology ). I am head of the post-master education program for psychologists in training for health care psychologist and acting head of the post-master education program for health care psychologists in training for clinical psychologist. My research and clinical interests focus on behavioral treatments for children with behavioral problems, including ADHD. I am actively working on the dissemination of scientific insights into practice and a member of Dutch ADHD guideline and practice standard groups. In the past years I was involved in the Psychosocial ADHD Interventions (PAINT) research group. The research of the PAINT group focusses on effective components of behavioral interventions, moderators of behavioral treatment response by conducting individual participant data meta analyses, and effectiveness of brief parent and teacher training programs for children with behavioral problems.
Declaration of potential conflict of interestsReceived research grants from ZonMw (The Netherlands Organisation for Health Research and Development); NWO (The Netherlands Organisation for Scientific Research); UMCG (University Medical Centre Groningen, The Netherlands).
Receives royalties as one of the editors of "Sociaal Onhandig" (published by Van Gorcum), a Dutch book for parents that can be used in parent training. Non-financial: is and has been involved in the development and evaluation of several behavioral interventions, without financial interests; has been a member of Dutch ADHD guideline groups; is an advisor of the Dutch Knowledge Centre for Child and Adolescent Psychiatry.Contact info -
Prof. van der Oord, Saskia (Belgium)
Faculty of Psychology and Educational Sciences, KU Leuven
http://lirias.kuleuven.be/cv?Username=U0062158
Work and interestsProf. Dr. Saskia van der Oord research is focused on ADHD in children and adolescents. Her research is focused on 1) improving effectiveness of current behavioral treatments by knowing more of effective treatment elements and for whom treatment works most 2) integrating knowlegde of experimental research of motivation and learning in ADHD into treatment 2) developing new treatments for ADHD (e.g. a sleep focused treatment for adolescents with ADHD) and experimentally testing these on effectiveness 3) reducing stigma for ADHD by (game-based )ADHD awareness interventions. She works as a clinical child psychologist/behavior therapist and supervises postmaster clinical psychology students in the Faculty’s assessment and intervention facility Praxis P. Also, she is head of the 4-year postmaster child and adolescent behavior therapy training.
Declaration of potential conflict of interestsN/A
Contact info -
Prof. Wong, Ian C. K. (United Kingdom)
University College London (UCL) and University of Hong Kong
https://www.pharma.hku.hk/Our-People/Professoriate/Head/Professor-Ian-CK-WONG/Professor-Ian-CK-WONG-Profile
Work and interestsProfessor Ian Wong has worked on the safety of psychotropic drugs since 1997. He has been highly successful in his application for research funding, amounting to several million pounds for psychopharmacology research. He has over 400 publications. Professor Wong has supervised more than 20 PhD students who investigated the safety of psychotropic drugs for the treatment of ADHD, anorexia, ASD, bipolar disorder, psychosis, and depression.
He has particular expertise in interrogating national and international healthcare databases, using sophisticated strategies that enable high-quality evidence-based information to be obtained. This has enabled him to have a significant impact in improving the safety and efficacy of the treatment of psychiatric disorders. Three recent examples of publications using these strategies with analysis of large databases were the Lancet Psychiatry paper showing wide variations in psychotropic drug prescribing across 65 countries and regions and recommending future improvement in practice and research for some lower-middle-income countries. His papers in the Lancet Child and Adolescent Health and JAMA Psychiatry showing that first-line medication for attention deficit hyperactivity disorder (methylphenidate) does not cause epilepsy or increased risk in suicidal behaviour. His BMJ and JAMA Internal Medicine papers showing that antidepressants and antipsychotic treatment during pregnancy does not increase the risk of attention deficit hyperactivity disorder in the offspring. Last but not least, Professor Ian Wong has developed a commercially available medicinal product for the treatment of acute prolonged seizures (Buccolam) via his spin-off company with the UCL and Great Ormond Street Hospital for Children. Buccolam is now used by patients with epilepsy throughout Europe.Declaration of potential conflict of interestsI have received research and educational grants from Amgen, Bayer, Bristol-Myers Squibb, GSK, Janssen, Novartis, Pfizer, the Hong Kong Research Grants Council, and the Hong Kong Health and Medical Research Fund, the National Institute for Health Research in England, European Commission, National Health and Medical Research Council in Australia.
I was a member of NICE ADHD Guideline Development Group in England.Contact info -
MD. Prof. Zuddas, Alessandro (Italy)
University of Cagliari, Dept Biomedical Sciences, Sect. Neuroscience & Clinical Pharmacology, Cagliari, Italy;
Child & Adolescent Neuropsychiatry, "A.Cao" Pediatric Hosptal, Cagliari
https://www.unica.it/unica/page/en/alessandro_zuddas
Work and interestsAlessandro Zuddas, MD, is currently Professor of Child Neuropsychiatry at the School of Medicine, University of Cagliari and Director of the Child & Adolescent Neuropsychiatry Unit a the “A.Cao” Paediatric Hospital, Cagliari, Italy.
His work integrates Developmental Psychopathology and Child & Adolescent Psychopharmacology approaching the study of the biological mechanism of neuro-developmental and mental health conditions in order to develop and validate innovative therapeutical strategies.
Main areas of interest are ADHD and other developmental disorders as well as Affective and conduct disorders.
He also coordinate the European Child & Adolescent Psychopharmacolgy Network (ECAPN) at EnprEMA.Declaration of potential conflict of interestsProf. Zuddas reported personal fees for being on advisory boards from Angelini, Servier, and Shire/Takeda; research grants from Acadia, Angelini, Janssen, Lundbeck, Otsuka, and Servier; and royalties from Giunti OS, Hogrefe Editore, and Oxford University Press.
Contact info
Working Groups
The EAGG has currently two active working groups:
Interventions to Improve Outcomes for Children and Adolescents with ADHD – An Integrative Approach. The purpose of this work is to integrate the evidence base in relation to different types of interventions for ADHD, taking account of the limitations of study designs and quality and consistency of evidence, in order to guide clinicians in their management of ADHD.
Network Meta-Analysis of Pharmacological Interventions for ADHD. Under the lead of Dr Cortese, the EAGG has been successful in compiling the most comprehensive database of RCTs of ADHD medications across the lifespan, including published and unpublished data. Based on this dataset, a network meta-analysis on the efficacy and tolerability of ADHD medications was published in 2018 (Cortese at al., Lancet Psychiatry, 2018). The dataset will be periodically updated and analysed with the most advanced approaches of evidence synthesis. An ongoing project focuses on a network meta-analysis aimed at comparing ADHD drugs in terms of individual side effects.
Planned & Past Activities
The EAGG has undertaken a series of authoritative and influential reviews of non-pharmacological treatments for ADHD:
Covering a wide range of behavioural, psychological dietary treatments:
- Sonuga-Barke et al., 2013
Covering treatment domain-specific follow-up analyses:
- Stevenson et al., 2013
- Daley et al. 2014
- Cortese et al., 2015
- Cortese et al 2016
The EAGG approach is distinctive in its methodological rigour and its attempts to deal systematically with the issue of outcome blinding by comparing “most proximal” (least blinded outcomes) with best “probably blinded” outcomes. Taking the best evidence the EAGG reviews found limited support for behavioural parent training, cognitive training or neuro-feedback as a treatment for core ADHD symptoms. Behavioural parent training was effective as a treatment for associated conduct problems while cognitive training and neuro-feedback appeared to improve some underlying cognitive functions. Dietary exclusions (additive colourings and flavourings) and supplements (free fatty acids) were associated with small but statistically significant benefits. Since these publications, new evidence has become available and updates of these meta-analyses are currently being planned.